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TRACE C2 Control

TRACE C2 Control - Continuous online monitoring and control

TRACE C2 Control is used for online monitoring of important substrates and metabolites in cultivations of microorganisms and cell lines.
Additionally, it provides direct PID and min/max-feed control with an integrated feed pump.

TRACE C2 Control provides continuous analysis independent of the type of cultivation (batch, fed-batch, continual cultivation). Due to its structured design and simple operating concept, routine analysis functions can be performed with only a brief introduction.

The device is connected to the bioreactor using preconfigured single use tubing sets including pumps and valves for precise control of all procedures rendering safe operation possible over long time periods. Its special design enables safe and economic continuous and long-term operations with almost no amount of maintenance and low installation size. For connection to the bioreactors TRACE Analytics GmbH offers its well-proven (single-use) dialysis sampling probes, bypass modules and filtration probes.

TRACE C2 Control is a compact and cost-efficient device which is controlled through a PC-software included in the package. With its interfaces the device can be easily connected to peripheral instruments and integrated in SCADA systems.

By combining the TRACE M4 peripheral device, the TRACE C2 Control can be extended to four measurement channels.


  • Timely and safe results without manual intervention
  • Integrated controller and feed pump
  • Improves process understanding through online analysis
  • Reduces process development time
  • Eliminates weekend and overnight manual sampling and offline analysis


  • Optimal monitoring and control of bioprocesses through online measurement
  • Glucose and Lactate
  • Methanol or Ethanol
  • Internal PID controller and feed pump or alternatively external pump
  • Single-use sensors and tubing manifolds
  • Compact design with full system integration
  • Stable biosensors
  • Cell-free sampling (dialysis or filtration)
  • Connection to different fermenter and single-use reactors

Technical data

  • Control by PC software supplied
  • PC for control: Operating system Windows XP, Windows 7, 8, 10, Windows Server 2012 R2
  • External power supply: 100..120 / 220..240 V~; 50/60 Hz
  • Interfaces: RS 232, Ethernet, OPC UA, Modbus TCP
  • Serial interface for external feed pump
  • Analog output 0..10V for external analog feed pump
  • Analog output 0..10 V, 0..20 mA; 4..20 mA
  • Dimensions (in mm): 120 x 170 x 200 (W x H x D)
  • Weight: 1.8 kg
  • Ambient conditions:
    • Temperature (15 - 35°C)
    • Humidity (10 - 90%)
  • Measuring principle enzymatic amperometric
  • Measuring range:
    • Glucose (0.1 to 40 g/L)
    • Lactate (0.05 to 5 g/L)
    • Methanol (0.5 to 20 g/L)
    • Ethanol (1 to 40 g/L)
  • Measurement frequency:
    • Dialysis (up to 30 measured values per hour = every 2 minutes)
    • Filtration (up to 60 measured values per hour = every minute)
  • Measurement deviation:
    • Glucose (<1.5% at 2 g/L)
    • Lactate (<1.5% at 1 g/L)
    • Methanol (<5% at 1 g/L)
    • Ethanol (<5% at 2 g/L)
  • Service life of the sensors 5000 measurements or 30 days

The device is available in identical form (without feeding pump) as
BioPAT® Trace through our distribution partner Sartorius Stedim Biotech GmbH.

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